J N Mark Glover Selected Research

Neoplasms (Cancer)

1/2021	Structural insights into DNA double-strand break signaling.
11/2019	Domain analysis of PNKP-XRCC1 interactions: Influence of genetic variants of XRCC1.
10/2019	Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
1/2017	Characterization of DNA Substrate Binding to the Phosphatase Domain of the DNA Repair Enzyme Polynucleotide Kinase/Phosphatase.
4/2016	RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment.
6/2009	Mutation of FOXL2 in granulosa-cell tumors of the ovary.
6/2009	Agrobacterium tumefaciens VirC2 enhances T-DNA transfer and virulence through its C-terminal ribbon-helix-helix DNA-binding fold.
2/2006	BRCA1 DNA-binding activity is stimulated by BARD1.
1/2006	Insights into the molecular basis of human hereditary breast cancer from studies of the BRCA1 BRCT domain.
6/2004	Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1.

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J N Mark Glover Research Topics

Disease

11	Neoplasms (Cancer) 01/2021 - 12/2003
4	Breast Neoplasms (Breast Cancer) 05/2015 - 12/2003
2	Ataxia Telangiectasia (Louis Bar Syndrome) 02/2024 - 07/2011
1	Obesity 01/2023
1	Hyperglycemia 01/2023
1	COVID-19 01/2022
1	Neurodevelopmental Disorders 01/2017
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Inflammation (Inflammations) 04/2016
1	Ovarian Neoplasms (Ovarian Cancer) 06/2010
1	Nijmegen Breakage Syndrome 10/2009

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2021 - 12/2003
5	DNA (Deoxyribonucleic Acid)IBA 11/2019 - 06/2009
2	EnzymesIBA 01/2023 - 01/2017
2	Peptides (Polypeptides)IBA 05/2015 - 06/2004
1	Nalpha- (2- naphthylsulfonyl)- 3- amidinophenylalanine- carboxymethylpiperazideIBA 02/2024
1	TransferasesIBA 01/2023
1	Coenzyme A (CoA)IBA 01/2023
1	Dopamine (Intropin)FDA LinkGeneric 01/2023
1	KetonesIBA 01/2023
1	Pimozide (Orap)FDA Link 01/2023
1	succinyl-coenzyme A (succinyl-CoA)IBA 01/2023
1	Antipsychotic Agents (Antipsychotics)IBA 01/2023
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022
1	GlucocorticoidsIBA 01/2022
1	Protein Phosphatase 1IBA 10/2019
1	4-aminophenylphosphate (PNPP)IBA 10/2019
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2017
1	UbiquitinIBA 04/2016
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 04/2016
1	ChromatinIBA 07/2012
1	Phosphotransferases (Kinase)IBA 07/2011
1	BRCA1 ProteinIBA 06/2010
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 10/2009
1	T-DNAIBA 06/2009
1	Peptide Hydrolases (Proteases)FDA Link 12/2003

Therapy/Procedure

2	Therapeutics 01/2021 - 01/2017